SINTESIS ASETIL ASKORBAT MELALUI ASETILASI TANPA PELARUT DAN KATALIS
Abstract
ABSTRACT
The preparation of acetyl ascorbate by acetylation without solvent and catalyst has been carried out. The preparation of acetyl ascorbate is carried out by reacting ascorbic acid with anhydrous acetic acid using a 1:1 mole ratio without solvent and catalyst. The acetylation reaction was carried out using the reflux method at 700C for 5 hours. The result of acetyl ascorbate acetylation is a yellow powder with a yield percentage of 71.8182%. The functional groups of the synthesized compound in the form of acetyl ascorbate were analyzed using a FT-IR spectrophotometer. The FT-IR analysis results show the functional groups OH, CH sp3, C=C, C=O ester and C-O-C ester. Based on these results it can be seen that acetyl ascorbate has been formed.
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References
[1] Song, Q.X., Y.Zhao, W.Q. Xu, W.Y. Zhou, D.Z. Wei. 2006. Enzymatic Synthesis of L-ascorbyl Linoleate in Organic Media. Bioprocess Biosyst eng 28:211-215.
[2] Winarsi, H. 2007. Antioksidan Alami dan Radikal Bebas Potensi dan Aplikasinya Dalam Kesehatan. Yogyakarta: Kanisius.
[3] Nisak, K. 2017. Sintesis Askorbil Palmitat dari Metil Palmitat dan Asetil Askorbat Melalui Reaksi Interesterifikasi Dengan Katalis Lipase). Samarinda: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman. 02(2): 204-208.
[4] Said, M., Agustria., Dimitra, A.U. 2017. Sintesis Poliester Melalui Reaksi Asetilasi Senyawa Poliol Minyak Jagung. Palembang: Jurusan Teknik Kimia Fakultas Teknik, Universitas Sriwijaya. No. 3. Vol 23. 199-207.
[5] Song, Q.X., D.Z. Wei., W.Y. Zhou.,W.Q. Xu, S.L Yang. 2004. Enzymatic Synthesis and Antioxidant Properties of L-ascorbyl Oleate and L-ascorbyl Linoleate. Biotevhnology Lett 26: 1777-1780.
[6] Karmee, S. K. 2009. Biocatalytic Synthesis of Ascorbyl Ester and Their Biotechnological Applications. Appl Microbiol Biotechnol. 81: 1013-1022.
[7] Daniel. 2009. Synthesis Alkanolamide Tetrehidroxy Octadecanoate Compound From Candle Nut Oil. Indo. J. Chem., 2009, 9 (2), 271-277.
[8] Daniel. 2009. Synthesis of Surfactans Dilauroyl Maltose Through Acetilation Reaction of Maltose Followed by Transesterification Reaction With Methyl Laurate. Indo. J. Chem., 2009, 9 (3), 445-45.