Isolasi Total Flavonoid Daun Pala (Myristica fragrans Houtt)
Abstract
Tumbuhan Pala (Myristica fragrans Houtt) termasuk dalam famili Myristicaceae. Tumbuhan ini secara etnobotani terbukti mempunyai aktivitas antibakteri. Penelitian tentang isolasi senyawa flavonoida (total flavonoida) uji aktivitas antibakteri daun Pala terhadap Staphilococcus aureus dan Escherrichia coli telah dilakukan. Ekstraksi 3 Kg (3000 g) daun Pala dengan metanol diperoleh ekstrak metanol 417,60 g (13,92%). Ekstrak metanol di larutkan ke dalam etil asetat diperoleh ekstrak etil asetat 104,1 g (5,96%). Hasil partisi ekstrak etil asetat dengan n-heksana diperoleh total flavonoid 32,76 g (31,47%). Hasil hirolisis total flavonoid dengan HCl 6% diperoleh 1,8 g total flavonoid (bebas glikon). Hasil uji aktivitas antibakteri ekstrak metanol dan ekstrak etil menunjukkan bahwa ekstrak etil asetat daun pala mempunyai aktivitas antibakteri terhadap Staphilococcus aureus dan Escherrichia coli, sedangkan ekstrak metanol tidak aktif.Downloads
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References
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Dorman, H. J. D., & Deans, S. G. 2004. Chemical Composition, Antimicrobial and in Vitro Antioxidant Properties of Monarda citriodora var. citriodora, Myristica fragrans, Origanum vulgare ssp. hirsutum, Pelargonium species, and Thymus zygis oils. Journal of Essential Oil Research, 16, 145e150.
Ginting, B. 2013. Prosiding Seminar Nasional Kimia 2013. Universitas Sumatera Utara Gupta, A.D., Vipin Kumar Bansal, Vikash Babu, Nishi Maithil. 2013. Chemistry, antioxidant and antimicrobial potential of nutmeg (Myristica fragrans Houtt), Journal of Genetic Engineering and Biotechnology.
Narasimhan, B., & Dhake, A. S. 2006. Antibacterial Principles from Myristica Fragrans Seeds. Journal of Medicinal Food, 9, 395e399.
Pillai, S., Roziahanim Mahmud, Wei Cai Lee, Shanmugapriya Perumal. 2012. Anti-parasitic Activity of Myristica fragrans Houtt. Essential Oil against Toxoplasma Gondii Parasite, sciverse science direct, APCBEE Procedia 2, 92 – 96.
Sulaiman, S.F., and Kheng L.O. 2012 Antioxidant and Anti Food-borne Bacterial Activities of Extracts from Leaf and Different Fruit Parts of Myristica Fragrans Houtt, Journal of Food Control.
Takikawa, A., Keiko Abe, Makiko Yamamoto, Shoko Ishimaru, Mari Yasui, Yoko Okubo, and Kumio Yokoigawa. 2002. Antimicrobial Activity of Nutmeg against Escherichia coli 0 157, Jpurnal of Bioscience and Bioengineering, Vol. 94, No. 4,3 15-320
Published
2016-04-26
How to Cite
GINTING, Binawati et al.
Isolasi Total Flavonoid Daun Pala (Myristica fragrans Houtt).
PROSIDING SEMINAR NASIONAL KIMIA, [S.l.], apr. 2016.
Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/prosiding/article/view/118>. Date accessed: 20 apr. 2024.
Section
ARTIKEL
Keywords
Pala (Myristica fragrans Houtt); Myristicaceae; total flavonoid; Staphilococcus aureus dan Escherrichia coli; antibakteri.
