PENGHAMBATAN AKTIVITAS α-GLUKOSIDASE DARI EKSTRAK METANOL BUNGA BUGENVIL (Bougainvillea glabra Choisy)

INHIBITION OF α-GLUCOSIDASE ACTIVITY FROM METHANOL EXTRACT OF BUGENVIL (Bougainvillea glabra Choisy) FLOWER

  • Intan Dessy Puspitasari Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman
  • Chairul Saleh Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman
  • Rita Hairani Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman
  • Ritbey Ruga Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman

Abstract

The test of Phytochemical screening and antidiabetic activity of methanol extract  of bugenvil (Bougainvillea glabra Choisy) flower against α-glucosidase inhibition have been conducted. This study aims to determine the content of secondary metabolite compounds and the effectiveness of the methanol extract of bugenvil flower against α-glucosidase activity. Phytochemical test showed that the methanol extract contained secondary metabolite compounds namely alkaloids, flavonoids, steroids, phenolics and saponins. By 50 µg/mL, the methanol extract of bugenvil flower can inhibit α-glucosidase activity with a percent inhibition value of 79.42% while acarbose as a positive control in this study exhibited antidiabetic activity against α-glucosidase of 99.30% at a concentration of 0.00006 µg/mL.

Keyword
Bougainvillea (Bougainvillea glabra Choisy) flower, Phytochemical Test, α-Glucosidase Inhibition.

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Published
2024-03-31
How to Cite
PUSPITASARI, Intan Dessy et al. PENGHAMBATAN AKTIVITAS α-GLUKOSIDASE DARI EKSTRAK METANOL BUNGA BUGENVIL (Bougainvillea glabra Choisy). JURNAL ATOMIK, [S.l.], v. 9, n. 1, p. 25-29, mar. 2024. ISSN 2549-0052. Available at: <https://jurnal.kimia.fmipa.unmul.ac.id/index.php/JA/article/view/1276>. Date accessed: 23 july 2024. doi: https://doi.org/10.30872/ja.v9i1.1276.
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