PEMANFAATAN FRAKSI ETANOL DAUN JARUM TUJUH BILAH (Pereskia bleo (Kunth) D.C) SEBAGAI INHIBITOR XANTIN OKSIDASE DALAM PEMBENTUKAN ASAM URAT

  • Ade Putri Hawiyah Sarwawan Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University
  • Saibun Sitorus Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University
  • Rahmat Gunawan Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University

Abstract

This research was conducted to determine the content of secondary metabolite contained in the extract and ethanol fraction of “Jarum tujuh bilah†leaves (Pereskia bleo (Kunth) DC) and and inhibition of xanthine oxidase activity obtained from the isolation of cow's milk. The xanthine oxidase activity is measured at a wavelength of 290 nm. The results of this research indicate that in the ethanol extract and fraction of “jarum tujuh bilah†leaves have the secondary flavonoids, alkaloids and phenolic compounds. The highest inhibition of xanthine oxidase activity in the ethanol extract of “jarum tujuh bilah†leaves was 91.67%, while the inhibition of allopurinol was 50% and the ethanol fraction of “jarum tujuh bilah†leaves was seven blades by 90%.

Keyword
Inhibition, Urid acid, Xanthine Oxidase

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References

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Published
2019-03-30
How to Cite
SARWAWAN, Ade Putri Hawiyah; SITORUS, Saibun; GUNAWAN, Rahmat. PEMANFAATAN FRAKSI ETANOL DAUN JARUM TUJUH BILAH (Pereskia bleo (Kunth) D.C) SEBAGAI INHIBITOR XANTIN OKSIDASE DALAM PEMBENTUKAN ASAM URAT. JURNAL ATOMIK, [S.l.], v. 4, n. 1, p. 45-49, mar. 2019. ISSN 2549-0052. Available at: <https://jurnal.kimia.fmipa.unmul.ac.id/index.php/JA/article/view/880>. Date accessed: 13 july 2024.
Section
Artikel