POTENSI ANTIBAKTERI EKSTRAK ETANOL MENIRAN  (Phyllanthus niruri L.) TERHADAP BAKTERI Streptococcus sobrinus DAN Salmonella typhi

Dea Rakasiwi; Winni Astuti; Eva Marliana

Dea Rakasiwi Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman
Winni Astuti Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman
Eva Marliana Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Mulawarman

Abstract

Meniran (Phyllanthus niruri L.) is one of the herb plants used as traditional medicine, such as toothache medicine and diarrhea medicine. The purposed of this study was to determined the type of secondary metabolites in the ethanol extract of meniran herb and to determined the minimum inhibitory concentration (MIC) value of the ethanol extract of meniran (Phyllanthus niruri L.) to Streptococcus sobrinus KCCM 11898 and Salmonella typhi ATCC 422. The ethanol extract of meniran was tested for phytochemicals. The MIC value of the ethanol extract of meniran herb for the test bacteria was obtained by varying the concentration of the ethanol extract of meniran herbs. Phytochemical test results showed that the ethanol extract of meniran herbs contains alkaloids, phenolics and steroids. The minimum inhibitory concentration value of the ethanol extract of meniran herb at the bacteria Streptococcus sobrinus KCCM 11898 and Salmonella typhi ATCC 422 each was 0.625%.

Keywords: Phyllanthus niruri L, minimum inhibitory concentration (MIC), Streptococcus sobrinus KCCM 11898, Salmonella typhi ATCC 422

Downloads

Download data is not yet available.

References

[1]Brooks, G. F., Jawetz, E., Melnick, J. L., Adelberg, E. A., dan Carroll, K. C. 2013. Medical Microbiology. 24th Ed. USA : Mc Graw Hill. 2007; 224 – 7.
[2]Haniastuti T. Dan Asih R. 2013. “Penurunan Produksi Asam dan pertumbuhan Bakteri Streptococcus sobrinus Setelah Terpapar Rebusan Daun Sirih Merah 10%”. dentika Dental Journal, Vol 17, No. 4, 2013: 324-328
[3]Nurmala, Virgiandhy I. G. N. and Liana D., 2015. Resistensi dan Sensitivitas Bakteri Terhadap Antibiotik di RSU dr. Soedarso PontianakTahun 2011-2013. eJKI, 3 (1), 21-28.
[4]Nopiyanti, N. dan Fitriani, L. 2019. “Inventarisasi Jenis-Jenis Tumbuhan Famili
Euphorbiaceae di Kecamatan Topos Kabupaten Lebong Provinsi
Bengkulu”. Jurnal Biosilampari: Jurnal Biologi, 1(2): 65-72.
[5]Setyohadi, R., Abdullah, AAHA., Narwastu, ACLK., 2011. Uji Efektifitas Antibakteri Ekstrak Meniran (Phylanthus niruri) Terhadap Streptococcus pyogenes Secara In Vitro. Skripsi. Malang: Universitas Brawijaya
[6]Supriyadi, H., dan Iftitah, D., 2009. Kegunaan Ekstrak Daun Meniran (Phylanthus niruri L.) Bagi Pengendalian Penyakit Ikan Akibat Infeksi Bakteri Aeromonas hydropila. Media Akuakultur Volume 4 No. 1
[7]Munfaati P. N., Ratnasari E., dan Trimulyono G., 2013, “Aktivitas Senyawa Antibakteri Ekstrak Herba Meniran (Phyllanthus niruri)
terhadap Pertumbuhan Bakteri Shigella dysenteriae Secara in Vitro”, Lentera Bio. Vol. 4 No. 1, Januari 2015: 64–71.
[8]Akbar, M. R. V., Budiarti, R. Y. dan Edyson. 2016. “Perbandingan Efektivitas
Antibakteri Antara Ekstrak Metanol Kulit Batang Kasturi dengan Ampisilin
Terhadap Staphylococcus aureus in Vitro”. Berkala Kedokteran Vol.12
No.1, Feb 2016:1-9.
[9]Suheri, F. L., Agus, Z. dan Fitria, I. 2015. “Perbandingan Uji Resistensi Bakteri
Staphylococcus aureus terhadap Obat Antibiotik Ampisilin dan Tetrasiklin”.
Andalas Dental Journa. Vol. 3, No. 1
[10]Darsana, I. G. O., Besung, I. N. K. dan Mahatmi, H. 2012. “Potensi Daun Binahong (Anredera Cordifolia (Tenore) Steenis) dalam Menghambat Pertumbuhan Bakteri Escherichia Coli secara In Vitro”. Indonesia Medicus Veterinus. 1(3): 337 – 351.
[11]Madduluri S., Rao K.B., Sitaram B. 2013. In vitro evaluation of antibacterial activity of five indigenous plants extract against five bacterial pathogens of human. International Journal of Pharmacy and Pharmaceutical Science; 5(4). h. 679-84.
[12]Pelczar, M.J. dan Chan, E.S. 2008. Dasar-Dasar Mikrobiologi Edisi ke-2. Jakarta:
Penerbit Universitas Indonesia.