Bioaktivitas Dan Kandungan Genus Callicarpa
Abstract
allicarpa L is one genus of the family Lamiaceae. Callicarpa consisting of approximately 150 species such as shrubs and trees. Various species of Callicarpa is widely used in traditional medicine and it was potentially as antinociceptive, antioxidant, antimicrobial and thrombolytic drugs. Based on various reports results of previous studies have found various types of secondary metabolites from plants Callicarpa such as terpenoids, steroids and flavonoids. Some of these compounds can be developed as an anti A. aegypti mosquito, Anopheles stephensi, and natural pesticides.
Keyword
Callicarpa, Traditional Medicine, Secondary Metabolites and Pentacyclic Triterpenoids
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References
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Rasikari, H. 2007. Phytochemistry and arthropod bioactivity of Australian Lamiaceae, PhD thesis, Southern Cross University, Lismore, NSW.
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Robbins, J. Beautyberry - Callicarpa Shrub Profile, University of Arkansas, United States Department ofAgriculture and County Governments Cooperating, diakses tanggal 25 november 2015.
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Verma, C., Bhatia, S. and Srivasta S., 2010, Traditional Medicine of the Nicobarese, Indian Journal of Traditional Knowledge, 9 (4), 779-785
Jone, W.P., Echeverri, T.L., Mi, Q., Chai, H.B., Soejarto, D.D., Cordel, G.A., Swanson, S.M., and Kinghorn A.D., 2007, Cytotoxic Cosntituents from Fruiting Branches of Callicarpa Americana Collected in Southern Florida, J. Nat. Prod. 70 (3), 372-377
Pons, L. 2006, Learning From Our Elders; Folk Remedy Yields Mosquito Thwarting Compound, Agriculturer Research, 54,(2), 15
Fasihuddin BA (1993). Medicinal plants used by Kadazan/Dusun community in Sabah. Sabah Museum J. 1: 15-30
Kshirsagar, R and Upadhyay, S., 2009, Free radical scavenging activity screening of medicinal plants from Tripura, Northeast India, Natural Product Radiance, 82 (2), 117-122
Yadav, V., Jayalakshmi, S. Singla, R.K. and Patra, A. 2011, Preliminary Assessment of Anti-Inflammatory Activity of Callicarpa macrophylla Vahl. Leaves Extracts, Indo-Global Journal of Pharmaceutical Sciences, 1(3): 219- 222
Hadi, S. and Bremner, J.B. 2001, Initial Studies on Alkaloids from Lombok Medicinal Plants, Molecules, 6,117-129
Xu J, Harrison LJ, Vittal JJ, Xu YJ, Goh SH., 2000, Four new clerodane diterpenoids from Callicarpa pentandra, J Nat Prod. 63(8):1062.
Cantrell, C.L., Klun, J.A., Bryson, C. T., Kobaisy, M. And Duke, S.O. 2005, tion and Identification of Mosquito Bite Deterrent Terpenoids from Leaves of American (Callicarpa americana) and Japanese (Callicarpa japonica) Beautyberry, J. Agric. Food Chem. 53,5948−5953
Carroll, J.F., Cantrell, C.L., Klun, J.A., and Kramer, M. 2007, Repellency of two terpenoid compounds isolated from Callicarpa Americana (Lamiaceae) against Ixodes scapularisand Amblyomma americanumticks, Exp Appl Acarol, 41:215–224
Cheng, H.H., Cheng, Y.B., Hwang, T.L., Kuo, H.K., Chen, C.H.,and Shen, Y.C. Randainins A–D, Based on Unique Diterpenoid Architectures, from Callicarpa randaiensis, J. Nat. Prod., 2015, 78 (8), 1823–1828.
Anaya, A.L., Mata, R., Sims, J.J., Coloma, A.G., Ortega, R.C., Guadano, A., Blanca, E. Bautista, B.E.H., Midland, S.L., RIOS, G. and Pompa, A.G. 2003, Allelochemical Potensial Of Callicarpa acuminate, Journal of Chemical Ecology, 29 (12), 2761-2776
Verma, R.K., Singh, A.K., Srivastava, P., Shanker, K., Kalra, A. and Gupta, M.M., 2009, Determination of Novel Plant Growth Promoting Diterpenes in Callicarpa macrophylla by HPLC and HPTLC, Journal of Liquid Chromatography & Related Technologies, 32: 2437–2450.
Verma, V.K., Siddiqui, N.U., and Aslam, M., 2012, A New Kaurane Diterpene from The Leaves of Callicarpa macrophylla, IRJP, 3 (5), 178-179.
Kawazu, K., Inaba, M., and Mitsui, T. 1967a, Studies on Fish-killing Component sof Callicarpa candicans Part1. Isolation of Callicarpone and its Toxicity to Fish, Agr. BioI. Chern., 31(4)- 494-497
Ono, M., Chikuba, T., Mishima, K., Yamasaki, T., Ikeda, T., Yoshimitsu, H., Nohara, T. 2009, A new diterpenoid and a new triterpenoid glucosyl ester from the leaves of Callicarpa japonica Thunb. var.luxurians Rehd, J Nat Med, 63:318–322.
Liu, Y.W., Cheng, Y.B., Liaw, C.C., Chen, C.H., Guh, J.H., Hwang, T.L., Tsai, J.S., Wang, W.B., and Shen, Y.C. 2012, Bioactive Diterpenes from Callicarpa longissima, J.Nat. Prod., 75 (4), 689-693
Wang, Y.M. Xiao, H., Liu, J.K., and Wang, F. 2010, New iridoid glycosides from the twigs and leaves of Callicarpa formosana var. formosana, Journal of Asian Natural Products Research, 12 (3), 220–226.
Mei, W.L., Han, Z., Cui, H.B., Zhao, Y.X., Deng, Y.Y., and Dai, H.F. 2009, A new cytotoxic iridoid from Callicarpa nudiflora, Natural Product Research, 1–6,
Chung, P.Y., Chung, L.Y., and Navaratnam, P., 2014, Potential targets by pentacyclic triterpenoids from Callicarpa farinosa against methicillin-resistant and sensitive Staphylococcus aureus, Fitoterapia, 94, 48–54
Chen, Z.C., Li, G., Xiang, Z.Z., and Zhan, L.Z. 2012, Triterpenes from Callicarpa integerrima Champ, Acta Pharmaceutica Sinica, 47 (1): 77−83.
Zhou, G.P, Yu, Y., Yuan, M.M., Ji, T., Fu, H.Z., and Zhong, R.J. 2015, Four New Triterpenoids from Callicarpa kwangtungensis, Molecules 2015, 20(5), 9071-9083.
Shihan, M.H., Mahmud, Z.A., Qais, N. and Riaz, M., 2015, Pharmacological Evaluation of Stem Bark of Callicarpa arborea Roxb., Dhaka Univ. J. Pharm. Sci. 14(1): 111-116
Rasikari, H. 2007. Phytochemistry and arthropod bioactivity of Australian Lamiaceae, PhD thesis, Southern Cross University, Lismore, NSW.
Munir, A.A. 1982, A Taxonomic Revision Of The Genus Callicarpa L. (Verbenaceae) In Australia, J. Adelaide Bot. Gard. 6(1): 5-39
Robbins, J. Beautyberry - Callicarpa Shrub Profile, University of Arkansas, United States Department ofAgriculture and County Governments Cooperating, diakses tanggal 25 november 2015.
Hargono, D. 1996, Sekelumit Mengenai Obat Nabati dan Sistim Imunitas, Cermin Dunia Kedokteran , 108, 5-9
Setyowati, F.M. 2010, Enofarmakologi Dan Pemakaian Tanaman Obat Suku Dayak Tunjung Di Kalimantan Timur, Media Litbang Kesehatan, XX (3), 104-112
Erwin, Nisa, R.A. and Daniel, 2015, Phytochemical Test, Toxicity and Antioxidant Activity Leaves Kerehau (Callicarpa longifolia Lam.) With DPPH Method, Indonesia Chimica Acta, 8 (1), 52-59
Novadiana, A., Erwin, Pasaribu, S.P., 2014, Isolasi Dan Identifikasi Senyawa Steroid Fraksi Kloroform Dari Fraksinasi Ekstrak Metanol Daun Kerehau (Callicarpa longifolia Lam.), Jurnal Kimia Mulawarman, 12 (1), 8-13.
Verma, C., Bhatia, S. and Srivasta S., 2010, Traditional Medicine of the Nicobarese, Indian Journal of Traditional Knowledge, 9 (4), 779-785
Jone, W.P., Echeverri, T.L., Mi, Q., Chai, H.B., Soejarto, D.D., Cordel, G.A., Swanson, S.M., and Kinghorn A.D., 2007, Cytotoxic Cosntituents from Fruiting Branches of Callicarpa Americana Collected in Southern Florida, J. Nat. Prod. 70 (3), 372-377
Pons, L. 2006, Learning From Our Elders; Folk Remedy Yields Mosquito Thwarting Compound, Agriculturer Research, 54,(2), 15
Fasihuddin BA (1993). Medicinal plants used by Kadazan/Dusun community in Sabah. Sabah Museum J. 1: 15-30
Kshirsagar, R and Upadhyay, S., 2009, Free radical scavenging activity screening of medicinal plants from Tripura, Northeast India, Natural Product Radiance, 82 (2), 117-122
Yadav, V., Jayalakshmi, S. Singla, R.K. and Patra, A. 2011, Preliminary Assessment of Anti-Inflammatory Activity of Callicarpa macrophylla Vahl. Leaves Extracts, Indo-Global Journal of Pharmaceutical Sciences, 1(3): 219- 222
Hadi, S. and Bremner, J.B. 2001, Initial Studies on Alkaloids from Lombok Medicinal Plants, Molecules, 6,117-129
Xu J, Harrison LJ, Vittal JJ, Xu YJ, Goh SH., 2000, Four new clerodane diterpenoids from Callicarpa pentandra, J Nat Prod. 63(8):1062.
Cantrell, C.L., Klun, J.A., Bryson, C. T., Kobaisy, M. And Duke, S.O. 2005, tion and Identification of Mosquito Bite Deterrent Terpenoids from Leaves of American (Callicarpa americana) and Japanese (Callicarpa japonica) Beautyberry, J. Agric. Food Chem. 53,5948−5953
Carroll, J.F., Cantrell, C.L., Klun, J.A., and Kramer, M. 2007, Repellency of two terpenoid compounds isolated from Callicarpa Americana (Lamiaceae) against Ixodes scapularisand Amblyomma americanumticks, Exp Appl Acarol, 41:215–224
Cheng, H.H., Cheng, Y.B., Hwang, T.L., Kuo, H.K., Chen, C.H.,and Shen, Y.C. Randainins A–D, Based on Unique Diterpenoid Architectures, from Callicarpa randaiensis, J. Nat. Prod., 2015, 78 (8), 1823–1828.
Anaya, A.L., Mata, R., Sims, J.J., Coloma, A.G., Ortega, R.C., Guadano, A., Blanca, E. Bautista, B.E.H., Midland, S.L., RIOS, G. and Pompa, A.G. 2003, Allelochemical Potensial Of Callicarpa acuminate, Journal of Chemical Ecology, 29 (12), 2761-2776
Verma, R.K., Singh, A.K., Srivastava, P., Shanker, K., Kalra, A. and Gupta, M.M., 2009, Determination of Novel Plant Growth Promoting Diterpenes in Callicarpa macrophylla by HPLC and HPTLC, Journal of Liquid Chromatography & Related Technologies, 32: 2437–2450.
Verma, V.K., Siddiqui, N.U., and Aslam, M., 2012, A New Kaurane Diterpene from The Leaves of Callicarpa macrophylla, IRJP, 3 (5), 178-179.
Kawazu, K., Inaba, M., and Mitsui, T. 1967a, Studies on Fish-killing Component sof Callicarpa candicans Part1. Isolation of Callicarpone and its Toxicity to Fish, Agr. BioI. Chern., 31(4)- 494-497
Ono, M., Chikuba, T., Mishima, K., Yamasaki, T., Ikeda, T., Yoshimitsu, H., Nohara, T. 2009, A new diterpenoid and a new triterpenoid glucosyl ester from the leaves of Callicarpa japonica Thunb. var.luxurians Rehd, J Nat Med, 63:318–322.
Liu, Y.W., Cheng, Y.B., Liaw, C.C., Chen, C.H., Guh, J.H., Hwang, T.L., Tsai, J.S., Wang, W.B., and Shen, Y.C. 2012, Bioactive Diterpenes from Callicarpa longissima, J.Nat. Prod., 75 (4), 689-693
Wang, Y.M. Xiao, H., Liu, J.K., and Wang, F. 2010, New iridoid glycosides from the twigs and leaves of Callicarpa formosana var. formosana, Journal of Asian Natural Products Research, 12 (3), 220–226.
Mei, W.L., Han, Z., Cui, H.B., Zhao, Y.X., Deng, Y.Y., and Dai, H.F. 2009, A new cytotoxic iridoid from Callicarpa nudiflora, Natural Product Research, 1–6,
Chung, P.Y., Chung, L.Y., and Navaratnam, P., 2014, Potential targets by pentacyclic triterpenoids from Callicarpa farinosa against methicillin-resistant and sensitive Staphylococcus aureus, Fitoterapia, 94, 48–54
Chen, Z.C., Li, G., Xiang, Z.Z., and Zhan, L.Z. 2012, Triterpenes from Callicarpa integerrima Champ, Acta Pharmaceutica Sinica, 47 (1): 77−83.
Zhou, G.P, Yu, Y., Yuan, M.M., Ji, T., Fu, H.Z., and Zhong, R.J. 2015, Four New Triterpenoids from Callicarpa kwangtungensis, Molecules 2015, 20(5), 9071-9083.
Shihan, M.H., Mahmud, Z.A., Qais, N. and Riaz, M., 2015, Pharmacological Evaluation of Stem Bark of Callicarpa arborea Roxb., Dhaka Univ. J. Pharm. Sci. 14(1): 111-116
Published
2016-07-26
How to Cite
-, Erwin.
Bioaktivitas Dan Kandungan Genus Callicarpa.
JURNAL KIMIA MULAWARMAN, [S.l.], v. 13, n. 2, july 2016.
ISSN 2476-9258.
Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JKM/article/view/220>. Date accessed: 18 apr. 2024.
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