AKTIVITAS ANTIKANKER SENYAWA PTEROKARPAN DARI KULIT BATANG AKA KALESI (Spatholobus ferrugineus)

  • Ratih Dewi Saputri State University of Surabaya (UNESA)
  • Muhammad Fadjar Aldin Airlangga University
  • Tjitjik Srie Tjahjandarie Airlangga University
  • Eva Marliana Mulawarman University
  • Mulyadi Tanjung Airlangga University
DOI: https://doi.org/10.30872/jkm.v20i2.920

Abstract




Tujuan dari penelitian ini adalah untuk mengisolasi dan menguji aktivitas antikanker senyawa pterokarpan dari kulit batang Spatholobus ferrugineus (Zoll. & Moritzi) Benth terhadap MCF-7 yaitu sel kanker payudara. Terdapat dua senyawa turunan pterokarpan yang berhasil diisolasi yaitu senyawa variabilin (1) and medikarpin (2). Kedua senyawa tersebut dikarakterisasi dengan instrument 1D dan 2D NMR yang menyatakan bahwa kedua senyawa yang berhasil diisolasi adalah senyawa 1 dan 2. Senyawa 1 dan 2 menunjukkan aktivitas antikanker dengan nilai IC50 2,73 dan 14,36 μg/mL.


Kata kunci : pterokarpan, antikanker, Spatholobus ferrugineus, MCF-7.




Keyword
Spatholobus ferrugineus, pterokarpan, antikanker, sel MCF-7

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References

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Published
2023-05-26
How to Cite
SAPUTRI, Ratih Dewi et al. AKTIVITAS ANTIKANKER SENYAWA PTEROKARPAN DARI KULIT BATANG AKA KALESI (Spatholobus ferrugineus). JURNAL KIMIA MULAWARMAN, [S.l.], v. 20, n. 2, p. 70-74, may 2023. ISSN 2476-9258. Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JKM/article/view/920>. Date accessed: 27 apr. 2024. doi: https://doi.org/10.30872/jkm.v20i2.920.
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Vol 20 No 2 (2023)
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