UJI AKTIVITAS INHIBISI AMILASE PADA TANAMAN Melicope YANG BERPOTENSI SEBAGAI ANTIDIABETES

  • Siti Nurjanah Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University
  • Eva Marliana Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University
  • Winni Astuti Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University

Abstract

The test of amylase inhibition activity of the leaves of Melicope lunu-ankenda and bark of Melicope glabra (BI.) T.G. Hartley extracts were done. The objective of this study was to determine in-vitro α-amylase inhibition activity against two samples by DNS method. The result showed that two samples of Melicope lunu-ankenda leaves and bark of Melicope glabra (BI.) TG Hartley displayed the enzyme inhibitory effect with percent inhibitions of 48.71% and 46.36%. Two sample extracts can inhibit amylase. It can be suggested that about sample were potential as antidiabetic agents.

Keyword
Melicope lunu-ankenda, Melicope glabra (BI.) T.G. Hartley, Amylase inhibition

Downloads

Download data is not yet available.

References

[1] Russel D. M. 2011. Bebas dari 6 penyakit paling mematikan. Yogyakarta: Media Pressindo (Anggota IKAPI).
[2] Ririn C. 2012. Pengaruh jumlah pasta tomat terhadap penurunan kadar gula darah pada mencit diabetes. Tesis. Fakultas Teknologi Industri Pertanian Pascasarjana Universitas Andalas.
[3] IDF. 2017. International Diabetes Federation Atlas 6th. Belgium: International Diabetes Federation.
[4] Amirta R., Angi E., Ramadhan R., Kusuma I., Wiati C dan Haqiqi M. 2017. “Potensi Pemanfaatan Macaranga”. Samarinda: Mulawarman University Press.
[5] Rahayu M., Sunarti S., Sulistiarini D., dan Prawiroatmojo S. 2006. Pemanfaatan tumbuhan obat secara tradisional oleh masyarakat lokal. Biodiversitas. 7(3):245-250.
[6] Al-Zuaidy H. M., Hamid A. A., Ismail A., Mohamed S., Razis A. F. A., Mumtaz W. M., dan Saleh Z. S. 2016. Potent antidiabetic activity metabolite profiling of Melicope luna-ankenda leaves. Journal of Food Science. 81:1080-1090.
[7] Ming N. K., But P. P., Alexander I. G., Thomas G. H., Kong Y., dan Waterman G. P. 1987. The biochemical systematics of Tetradium, Euodia and Melicope an their significance in the Rutaceae. Journal of Biochemical Systematics and Ecology. 15:587-593.
[8] Harborne J. B. 1998. Phytochemical Methods a Guide to Modern Techniques of Plants Analysist. London: Chapman &Hall.
[9] Butala A. M., Kupuni K. K. S., dan Vishnuprasad. 2017. Ayurvedic antidiabetic inhibits alpha-amylase, alpha-glukosidace and suppresss adipogenic activity in vitro. Journal of Ayurveda and Integrative Medicine. 8:145-151.
[10] Sazci A., dan Erenler K. 1986. Detection of cellulolytic fungsi by using congo red as an: a comparative study with the dinitrosalicyclick acid reagent method. Journal of Applied Bacteriology. 61:559-562.
[11] Sangi M., M. R. J. Runtuwene., H. E. I. Simbala dan V. M. A. Makang. 2008. Analisis fitokimia tumbuhan obat di Kabupaten Minahasa Utara. Chem. Prog., 1(1):47-53.
[12] Miller G. L. 1959. Use of dinitrosalicylic acid reagent of determination of reducing sugar. Anal. Chem. 31:246-248.
[13] Arif T., Gahlaut A., Sharma B., Dabur R., Kumar V. 2013. Antidiabetic agents from medicinal plants: A Review. Chemical Biology Letters. 1(1): 1-13.
[14] Brahmachari G. 2011. Bio-flavonoids with promising antidiabetic potencials: A critical survey. Research Signpost India. 37(2): 187-212.
[15] Hanefeld M., Koehler C., Schaper F., Fuecker K., Henkel E. 1999. Postprandial plasma glucose is an independent risk factor for increased carotid intima-media thickness in nondiabetic individuals. Atherosclerosis. 144(1): 229-235.
Published
2021-01-06
How to Cite
NURJANAH, Siti; MARLIANA, Eva; ASTUTI, Winni. UJI AKTIVITAS INHIBISI AMILASE PADA TANAMAN Melicope YANG BERPOTENSI SEBAGAI ANTIDIABETES. JURNAL ATOMIK, [S.l.], v. 5, n. 2, p. 94-98, jan. 2021. ISSN 2549-0052. Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JA/article/view/878>. Date accessed: 12 apr. 2021.
Section
Artikel