Macaranga hullettii King ex Hook.f : SUMBER FLAVONOID

  • Aditiya Hadi Ryan Pramana Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University
  • Eva Marliana Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University
  • Ritbey Ruga Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University

Abstract

Flavonoid compound had been isolated and characterized on fraction ethyl acetate of Macaranga hullettii King ex Hook.f leaves. The separation process in fraction ethyl acetate was performed using vacuum and gravity column chromatography with a gradient polarity method. The isolate was characterized as MH-1 flavonoid compound in the yellow crystals and 0.0432 g. Analysis of MH-1 with spectrophotometer UV showed two peaks at λ 268.46 (band II) and 340 nm (band I). Analysis of MH-1 with spectrophotometer IR showed  OH functional groups, C-O-C, C=O, aliphatic C-H, aromatic C-H, and aromatic C=C. The MH-1 is assumed to be a flavonoid.

Keyword
Flavonoids, Macaranga hullettii King ex Hook.f, and Isolation

Downloads

Download data is not yet available.

References

[1] Joseph J. Magadula. 2014. Phytochemistry and pharmacology of the genus Macaranga: A review. Tanzania: Department of Natural Products Development and Formulations, Institute of Traditional Medicine, Muhimbili University. 8:489-502.
[2] Slik J., Priyono and V. P. C, W. 2000. Key to the Macaranga thou. and Mallotus lour. species (Euphorbiaceae) of East Kalimantan Indonesia. Singapore: Garden’s Bulletin.
[3] Tanjung M., Hakim E. H., Elfahmi Latip, J., & Syah, Y. M. 2012. Dihydroflavonol and flavonol derivatives from Macaranga recurvate. Natural Product Communications, 7(10):1309–1310.
[4] Syah Y. M., Hakim E.H., Achmad S. A., Hanafi M., and Ghisalberti E. 2009. isoprenylated flavanones and dihydrochalcones from Macaranga trichocarpa. Natural Product Communications. 4:63–67.
[5] Sastrohamidjojo H. 1996. Sintesis bahan alam. Yogyakarta: UGM Press.
[6] Jang D. S., Cuendet M., Hawthorne M. E., Kardono L. B. S., Kawanishi K., Fong, H. H. S., Mehta R. G., Pezzuto J. M. dan Kinghorn A. D. 2002. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2. Phytochemistry. 61:867-872.
[7] Rismawati. 2018. Uji fitokimia dan antibakteri pada ekstrak metanol, fraksi n-heksan, fraksi etil asetat dan fraksi metanol sisa daun Macaranga hullettii King ex Hook.f. Skripsi. Samarinda: FMIPA Kimia Universitas Mulawarman.
[8] Atun S. 2014. Metode isolasi dan identifikasi struktur senyawa organik bahan alam. Jurnal Jurusan Pendidikan Kimia FMIPA Universitas Negeri Yogyakarta. 8:8-9.
[9] Tasmin N., Erwin dan Kusuma I. W. 2014. Isolasi, identifikasi dan uji toksisitas senyawa flavonoid fraksi kloroform dari daun Terap (Artocarpus odoratissimus Blanco). Skripsi. Universitas Mulawarman.
[10] Markham R. K., T. J Mabri dan M. B Thomas. 1970. The systematic identification of flavonoids. Berlin, Heidelberg. New York.
[11] Supratman U. 2010. Elusidasi Struktur Senyawa Organik. Bandung: Widya Padjadjaran.
Published
2020-09-28
How to Cite
PRAMANA, Aditiya Hadi Ryan; MARLIANA, Eva; RUGA, Ritbey. Macaranga hullettii King ex Hook.f : SUMBER FLAVONOID. JURNAL ATOMIK, [S.l.], v. 5, n. 1, p. 43-45, sep. 2020. ISSN 2549-0052. Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JA/article/view/944>. Date accessed: 31 oct. 2020.
Section
Artikel