Aktivitas Antioksidan Senyawa Flavonoid Dari Macaranga pearsonii Merr.

  • Eva Marliana Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman
  • Tjitjik Srie Tjahjandarie Fakultas Sains dan Teknologi Universitas Airlangga Surabaya
  • Mulyadi Tanjung Fakultas Sains dan Teknologi Universitas Airlangga

Abstract

Tiga senyawa flavanon , 4’-O-metil-8-isoprenileriodiktiol (1), 4’-O-metil-8-isoprenilnaringenin (2) and Lonkokarpol A  (3) , telah diisolasi dari ekstrak metanol daun  Macaranga pearsonii Merr. Elusidasi struktur senyawa berdasarkan data  spektroskopi  UV, 1D and 2D NMR, and HREISMS. Senyawa 1 – 3 ditentukan aktivitas antioksidannya terhadap peredaman radikal bebas 2,2-diphenyl-1-picrylhydrazyl (DPPH), dengan nilai  IC50 adalah 536,89 μM, 1226,11 μM dan 426,43 μM.

Keyword
Flavonoid, Macaranga pearsonii Merr, Antioksidan

Downloads

Download data is not yet available.

References

Slik JWF, Priyono, Welzen vPC. 2000. Key to the Macaranga Thou. And Mallotus Lour. Species (Euphorbiaceae) of East Kalimantan, Indonesia. Garden’s Bulletin Singapore 52: 11-87.

Tanjung M, Hakim EH, Elfahmi, Latip JM, Syah YM. 2012. Dihidroflavonol and Flavonol Derivatives from Macaranga recurvata. J Nat Prod Comm 7(10): 1309-1310.

Syah YM, Hakim EH, Achmad SA, Hanafi M, Ghisalberti EL. 2009. Isoprenylated Flavanones and Dihydrochalcones from Macaranga trichocarpa. J Nat Prod Comm 4: 63-67.

Zakaria I, Ahmat N, Jaafar FM, Widyawaruyanti A. 2012. Flavonoids with Antiplasmodial and Cytotoxic Activities of Macaranga triloba. J Fitoterapia 83: 968-972.

Versiani MA, Diyabalanage T, Ratnayake R, Henrich CJ, Bates SE, McMahon JB, Gustafson KR. 2011. Flavonoids from Eight Tropical Plant Species That Inhibit the Multidrug ABCG2, J Nad Prod 74: 262-266.

Agustina W, Juliawaty LD, Hakim EH, Syah YM. 2012. Flavonoid from Macaranga Lowi., ITB J Sci 44 A (1) : 13-18.

Tanjung M, Hakim EH, Mujahidin D, Hanafi M, Syah YM. 2009. Macagigantin, a Farnesylated Flavonol from Macaranga gigantea. J Asian Nat Prod Res 11: 929-932.

Syah YM, Ghisalberti EL. 2010. Phenolic Derivatives with an Irregular Sesquiterpenyl Side Chain from Macaranga pruinosa. J Nat Prod Comm 5: 219-222.

Tanjung M, Mujahidin D, Hakim EH, Darmawan, Syah, YM. 2010. Geranylated flavonols from Macaranga rhizinoides. J Nat Prod Comm 5(8): 1209-1211.

Jang DS, Cuendet M, Pawlus AD, Kardono LBS, Kawanishi, K, Farnsworth NR, Fong HHS, Pezzuto JM, Kinghorn AD. 2004. Potential Cancer Chemopreventive constituents of the Leaves of Macaranga triloba, J Phytochem 65: 345-350.

Yoder BJ. 2007. Isolation and Structure Elucidation of Cytotoxic Natural Products from The Rainforest of Madagascar and Suriname, Disertation,Faculty of The Virginia Polytecnic Institute and State University.

Kulisic T, Radonic A, Katalinic V, Milos M. 2004. Use of Different Methods for Testing Antioxidative Activity of Oregano Essential Oil, J Food Chem 85: 633-640.

Innok P, Rukachaisirikul T, Suksamrarn A. 2009. Flavanoids and Pterocarpans from the Bark of Erythrina fusca, Chem Pharm Bull 57(9): 993-996.

Seyoum A, Asres K, El-Fiky FK. 2006. Structure-Radical Scavenging Activity Relationships of Flavonoids, J. Phytochem. 65: 2058-2070.
Published
2016-06-14
How to Cite
MARLIANA, Eva; TJAHJANDARIE, Tjitjik Srie; TANJUNG, Mulyadi. Aktivitas Antioksidan Senyawa Flavonoid Dari Macaranga pearsonii Merr.. JURNAL KIMIA MULAWARMAN, [S.l.], v. 13, n. 2, june 2016. ISSN 2476-9258. Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JKM/article/view/206>. Date accessed: 24 apr. 2024.
Citation Formats
Issue
Vol 13 No 2 (2016)
Section
Artikel

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

This license requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, even for commercial purposes. If others remix, adapt, or build upon the material, they must license the modified material under identical terms.

  • BY: Credit must be given to you, the creator.
  • SA: Adaptations must be shared under the same terms.

    •