Antioksidan KUMARIN TERISOPRENILASI DAN ALKALOID INDOL DARI KULIT BATANG Zanthoxylum ovalifolium TUTCHER

Zanthoxylum ovalifolia

  • Mulyadi Tanjung Universitas Airlangga

Abstract

Two isoprenylated coumarins, imperatorin (1),  isopimpinelin (2) and one indol alkaloid compound,  canthine-6-one (3) were isolated from the stem bark of Zanthoxylum ovalifolium Tutcher. Their structures were determined  based on spectroscopic data such as UV, IR, MS and NMR.  Imperatorin (1) showed high activity toward DPPH radical and isopimpinelin (2) and chantine-6-one (3) has moderate activity.

Keyword
Zanthoxylum ovalifolium, coumarin, alkaloid, antioxidant

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References

Heyne, K., 1987. Tumbuhan Berguna Indonesia, Jilid II, Badan Penelitian dan Pengembangan Kehutanan, Departemen Kesehatan Republik Indonesia, Jakarta.
Marliana, E., Tjahjandarie, T.S., Tanjung, M., 2016. Aktivitas antioksidan senyawa flavonoid dari Macaranga pearsonii Merr. J. Kimia Mulawarman. 13(2): 97-100.
Muller, M., Byres, M., Jaspars, M., Kumarasamy, Y., Middleton, M., Nahar, L., Shoeb, M., Sarker, S.D., 2004, 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica, Acta Pharm, 54, 277-285.
Negi, J.S., Bisht, V.K., Bhandari, A.K., Singh, P., Sundriyal, R.C., 2011, Chemical constituents and biological activities of the genus Zanthoxylum: A review, African J.Pure and Applied Chem., 5(12), 412-416.
Siridechakorn, I., Laphookhieo, S., 2012, Chemical constituens from Feronia limonia roots, Chem. Nat. Compd, 48 (2), 308-309
Soriano-Agaton, F., Lagoutte, D., Poupon, E., Roblot, F., Fournet, A.,Gantier, J., Hocquemiller, R., 2005, Extraction, hemisynthesis, and of canthine-6-one analogues. Evaluation of their antifungal activities. J. Nat. Prod, 68(11), 1581-1587.
Tanjung, M.; Rachmadiarti, F.; Saputri, R.D.; Tjahjandarie, T.S. Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm. Nat.Prod. Res 2017, 1-6, http://dx.doi.org/10.1080/14786419.2017.1378215
Tanjung, M., Saputri, R.D., Tjahjandarie, T.S., 2017. 4-Methoxy-3-(3-methylbut-2-en-1-yl)-7-((3-methylbut-2-en-1-yl)oxy) quinolin-2(1H)-one from Melicope moluccana T.G. Hartley. Molbank. M939. 2: 1-5.
Tanjung, M; Fitriati, F.F.; Saputri, D.S;. Tjahjandarie, T.S. Antimalarial and antioxidant of isoprenylated coumarins from the stem bark of Mesua borneensis L. J Biol Active Prod from Nature. 2016. 6:95-100.
Tanjung, M., Saputri, R.D., Tjahjandarie, T.S., 2014. Antioxidant activity of two isomeric benzoxepin derivatives from the stem bark of Bauhinia aculeata L. J. Chem. Pharm. Res. 6: 705-708.
Tanjung, M., Tjahjandarie, T.S., Sentosa, M.H., 2013. Antioxidant and cytotoxic agent from the rhizomes of Kaempferia pandurata. Asian Pacific J. Tropical Disease. 3(5): 401-404.
Tjahjandarie, T.S.; Saputri, R.D.; Tanjung, M. 2017. 5,9,11-Trihydroxy-2,2-dimethyl-3-(2-methylbut-3-en-2-yl)pyrano[2,3-a] xanthen-12(2H)-one from the stem bark of Calophyllum tetrapterum Miq. Molbank. M936. 1: 1-5.
Tjahjandarie, T.S.; Saputri, R.D.; Tanjung, M. 2016. Oxygeranylated coumarins from the root of Limonia accidisima L. and their DPPH radical scavenging activity.Der Pharmacia Lettre. 8(20): 33-36.
Tjahjandarie, T.S., Tanjung, M., 2015. Lead compound antimalaria dan antioksidan senyawa alkaloid, flavonoid, dan kumarin dari Limonia accidisima L.. Laporan Akhir Penelitian Unggulan Perguruan Tinggi, Universitas Airlangga. 1-45.
Published
2018-05-30
How to Cite
TANJUNG, Mulyadi. Antioksidan KUMARIN TERISOPRENILASI DAN ALKALOID INDOL DARI KULIT BATANG Zanthoxylum ovalifolium TUTCHER. JURNAL KIMIA MULAWARMAN, [S.l.], v. 15, n. 2, p. 76-82, may 2018. ISSN 2476-9258. Available at: <http://jurnal.kimia.fmipa.unmul.ac.id/index.php/JKM/article/view/587>. Date accessed: 18 aug. 2018. doi: https://doi.org/10.30872/jkm.v15i2.587.
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Artikel